When it comes to blue eyes, you can’t always rely on your Husky puppy’s pedigree to tell you whether he’s a Husky or a mixed breed. Other breeds can have blue eyes, too, including Border Collies and small dogs with thin coats. Blue eyes are sometimes a sign of heterochromia, a condition that occurs in humans but is very common in some dog breeds, including Huskies.
Heterochromia
Husky puppies with blue eyes can also have brown eyes. The brown iris blends with the black pupil. The green-eyed husky is an extremely rare color, a transitional state from blue to brown, which the dog gets stuck on and stays for the remainder of his life. Heterochromia in husky puppies can be inherited or acquired through genetics, but it is a rare trait.
Heterochromia in husky pups is the result of a different mutation than the merle or albino canine gene. This means that a husky can have either blue or brown eyes regardless of its coat color. However, this does not necessarily mean that a blue-eyed husky is more likely to develop eye disorders than a brown-eyed husky.

Genetic mutation of the ALX4 gene
Husky dogs have a characteristic color that sets them apart from most other dog breeds: blue eyes. This characteristic results from a genetic mutation in the ALX4 gene. This gene causes a reduction in the production of pigment in the eye, making the eyes appear blue. Blue eyes are common in huskies and occur in approximately 40% of the litter. Though this mutation has no effect on the overall color of the dog’s coat, it does make its puppy appear distinctively blue.
Several genetic studies have linked blue eyes in husky puppies with a mutation in the ALX4 gene. This study was conducted at the Wester University of Health Sciences. The study identifies the ALX4 gene, which is found on canine chromosome 18.
XPRA affects the retina
PRA, or progressive retinal atrophy, is a hereditary disease that attacks the retina of a husky puppy. The disease causes gradual deterioration of photoreceptor cells in the retina, eventually resulting in blindness in affected dogs. Although it is often detected in puppies, the condition can also appear in adult dogs, including husky puppies. Some dogs may show symptoms of the disease immediately, while others may not be affected at all. As the disease progresses, the eyes of affected puppies become opaque and cataracts form in the center of the eye.
The progression of PRA affects both rod and cone cells in the retina, which are responsible for vision in dim light. Fortunately, the disease is not painful for the dog. A veterinarian can see the affected area using an ophthalmoscope to examine the retina. A veterinarian can also detect thinning in the retina, abnormal blood vessels, and other signs of this eye disease. Even subtle symptoms of the disease can warrant a referral to a veterinary ophthalmologist.
Pembroke Welsh corgis
There are two types of Welsh Corgis. Pembroke Welsh corgis and Cardigan Welsh corgis are similar but have slightly different appearances. They have similar brains, body shapes, and herding abilities. However, Pembroke Welsh corgis have blue eyes. They are also very intelligent and are great with children. If you’re considering getting one for your family, you can look for one in shelters or rescue groups.
The Pembroke Welsh corgi is the younger of the two breeds. They are descended from the Cardigan corgi, a breed that was developed earlier in Wales. Flemish weavers brought the pembroke to Wales in the 10th century. This breed is closely related to the Swedish Valhunds, which were brought to Wales by the Vikings. Their blue eyes are a sign of royalty.
Border collies
Blue-eyed Border collies are striking, gorgeous pets. Whether you’re thinking of a show dog or breeding your dog to be an all-blue breeder, you’ll love the beautiful blue eyes of this versatile breed. If you have been on the fence about getting a border collie, here are some facts you need to know. Blue-eyed Border collies are highly sought after. They can make stunning pets, and some even end up as all-blue breeders!
Blue eyes in border collies are genetic. The dog has two dominant genes that affect the color of their eyes. The pups inherit this trait from both parents. Although the pups will have brown eyes, they are still more likely to have blue eyes than brown. This characteristic is called heterozygous, meaning that both parents have the gene for blue eyes. However, there are exceptions, such as puppies born with blue eyes.
Pembroke Welsh corgis have blue eyes
As the name suggests, Pembroke Welsh corgis have gorgeous blue eyes. The breed is well-known for its high energy level, and this can make them a good watchdog. These dogs require daily walks and active play sessions. Those who are looking for a family dog should consider one of these dogs. Their size and fast pace make them a great companion for any household. Here are a few reasons to consider a Pembroke as a pet.
While having blue eyes is a sign of a healthy dog, it does not mean your Pembroke will suffer from any health problems. Eye problems are highly dependent on the pedigree’s merle gene status. Double merles have a higher risk of eye problems and overall health problems. Double-merles are created by breeding two merles. This means that half the litter inherits the merle gene, while the other half is born with a blue eye. This makes double-merles prone to many diseases.